Science N 6601 2022-07-01

Q1:Synthetic regulatory reconstitution reveals principles of mammalianHoxcluster regulation

Q2:Mutations linked to neurological disease enhance self-association of low-complexity protein sequences

Q3:Zonated leucine sensing by Sestrin-mTORC1 in the liver controls the response to dietary leucine

Q4:Conservation and divergence of cortical cell organization in human and mouse revealed by MERFISH

Q5:A specific circuit in the midbrain detects stress and induces restorative sleep

Q6:Ancient DNA reveals five streams of migration into Micronesia and matrilocality in early Pacific seafarers

Q7:Microglia-mediated degradation of perineuronal nets promotes pain

Q8:The microbiome and gut homeostasis

Q9:Cenozoic evolution of deep ocean temperature from clumped isotope thermometry

Q10:Global fast-traveling tsunamis driven by atmospheric Lamb waves on the 2022 Tonga eruption

Q11:Atmospheric waves and global seismoacoustic observations of the January 2022 Hunga eruption, Tonga

Q12:Locking volatile organic molecules by subnanometer inorganic nanowire-based organogels

Q13:Pleiotropic effects of trans-regulatory mutations on fitness and gene expression

Q14:Soft, bioresorbable coolers for reversible conduction block of peripheral nerves

Q15:Tectonic degassing drove global temperature trends since 20 Ma